Neuroscience
EGR1 Blocking Peptide
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| CSTコード |
包装 |
希望納入価格 (円) |
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| #1015S | 100 μg | 16,000 | |
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EGR1抗体製品一覧
| 使用目的 | |
| EGR1 (15F7) Rabbit mAb (#4153)の反応をブロックし、抗体の反応特異性を確認するために使用 |
IHC-P (paraffin)

Immunohistochemical analysis of paraffin-embedded mouse brain using EGR1 (15F7) Rabbit mAb #4153 in the presence of control peptide (left) or EGR1 Blocking Peptide (right).
EGR family members are transcriptional factors that contain three repetitive zinc finger DNA binding domains which bind to EGR response elements (ER) to regulate target gene expression (1). The expression of EGR family members is induced by growth factors, with EGR1 expression being induced by NGF (1,2). Increased EGR1 expression activates transcription of other signaling molecules, including CDK5 and tyrosine hydroxylase, and exerts long term effects on neural cell growth and differentiation (2,3).
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O'Donovan, K.J. et al. (1999) Trends Neurosci. 22, 167-173.
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Harada, T. et al. (2001) Nat. Cell Biol. 3, 453-459.
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Papanikolaou, N.A. and Sabban, E.L. (2000) J. Biol. Chem. 275, 26683-26689.