Glucose / Energy Metabolism
Insulin (C27C9) Rabbit mAb |
イイネ!(0) |
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| CSTコード | 包装 | 希望納入価格 (円) |
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|---|---|---|---|---|
| #3014S | 100 μL | 46,000 | ログインすると国内在庫状況がご確認いただけます。
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下記ステップについては、データシートの右側もあわせてご参照ください。
IHC-P: 抗体希釈液 / 抗原賦活化
| 用途(希釈倍率) | |
|---|---|
| 免疫組織染色(パラフィン)(1:400)、免疫蛍光染色(IF-F)(1:400)、免疫蛍光細胞染色(IF-IC)(1:100)、フローサイトメトリー(1:100) |
| 種交差性 | |
|---|---|
| ヒト、マウス、ラット |
| 特異性・感度 | |
|---|---|
| 内在性レベルのInsulin タンパク質を検出します。 |
| 検出タンパク質の分子量 | |
|---|---|
| 6 kDa |
| 使用抗原 | |
|---|---|
| ヒトのInsulin タンパク質由来の配列(合成ペプチド) |
| 抗体の由来 | |
|---|---|
| ウサギ |
| 貯法 | |
|---|---|
| -20℃ |
| 社内データ |
|---|
IHC-P (paraffin)

Immunohistochemical analysis of paraffin-embedded human pancreas, showing the staining of β cells, using Insulin (C27C9) Rabbit mAb.
IHC-P (paraffin)

Immunohistochemical anaylsis of paraffin-embedded mouse pancreas, showing staining of β cells, using Insulin (C27C9) Rabbit mAb.
IHC-P (paraffin)

Immunohistochemical analysis of paraffin-embedded rat pancreas, showing staining of β cells, using Insulin (C27C9) Rabbit mAb.
Flow Cytometry

Flow cytometric analysis of HeLa cells (blue) and β-TC-6 cells (green) using Insulin (C27C9) Rabbit mAb.
IF-IC

Confocal immunofluorescent analysis of β-TC-6 (left) and C2C12 cells (right) using Insulin (C27C9) Rabbit mAb (green). Actin filaments have been labeled with DY-554 phalloidin (red). Blue pseudocolor = DRAQ5® #4084 (fluorescent DNA dye).
IF-F

Confocal immunofluorescent analysis of rat pancreas using Insulin (C27C9) Rabbit mAb (green). Blue pseudocolor = DRAQ5® #4084 (fluorescent DNA dye).
| バックグラウンド |
|---|
The maintenance of glucose homeostasis is an essential physiological process that is regulated by hormones. An elevation in blood glucose levels during feeding stimulates insulin release from pancreatic β cells through a glucose sensing pathway (1). Insulin is synthesized as a precursor molecule, proinsulin, which is processed prior to secretion. A- and B-peptides are joined together by a disulfide bond to form insulin, while the central portion of the precursor molecule is cleaved and released as the C-peptide. Insulin stimulates glucose uptake from blood into skeletal muscle and adipose tissue. Insulin deficiency leads to type 1 diabetes mellitus (2).
| 使用例 | |
|---|---|
| 製品をご使用いただいて研究を発表されましたら、ぜひお知らせください。 |
| 関連製品 | |
|---|---|
| 2760 Glucagon Antibody | |
| 4590 Insulin Antibody | |
| 4593 C-Peptide Antibody | |
| 8112 SignalStain® Antibody Diluent |
本製品は試験研究用です。
