Antibody Sampler Kits
Jak Isoform Sampler Kit |
イイネ!(0) |
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| CSTコード | 包装 | 希望納入価格 (円) |
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|---|---|---|---|---|
| #9945S | 1 Kit | 56,000 | ログインすると国内在庫状況がご確認いただけます。
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- 3230:
- Flow IHC / Paraffin Immunofluorescence Immunoprecipitation Western Blotting
- 3344:
- IHC / Paraffin Immunoprecipitation Western Blotting
- 3775:
- Western Blotting
| キット内容 | 容量 | 用途 | 種交差性 | 検出タンパク質の分子量 | Isotype |
|---|---|---|---|---|---|
| Jak1 (6G4) Rabbit mAb #3344 | 40 µl | W IP IHC-P | H M R (Mk) (Dg) (Pg) | 130 | Rabbit IgG |
| Jak2 (D2E12) XP® Rabbit mAb #3230 | 40 µl | W IP IHC-P IF-IC F | H M R (Hm) (Mk) (C) (X) (B) (Dg) (Pg) (Hr) | 125 | Rabbit IgG |
| Jak3 Antibody #3775 | 40 µl | W | H | 115 | Rabbit |
| Anti-rabbit IgG, HRP-linked Antibody #7074 | 100 µl | Goat |
| 貯法 | |
|---|---|
| -20℃ |
| ※括弧付きの動物種は配列が100%相同であるため反応すると推定されます。 |
| 社内データ |
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Western Blotting

Western blot analysis of extracts from K562, THP-1, TF-1 and BaF3 cell lines using Jak2 (D2E12) XP® Rabbit mAb #3230.
Western Blotting

Western blot analysis of extracts from ACHN, SR, CTLL-2 and PC12 cell lines using Jak1 (6G4) Rabbit mAb #3344.
Western Blotting

Western blot analysis of recombinant proteins containing the kinase domain of Jak1, Jak2 and Jak3 (5 ng each), using Jak3 Antibody #3775.
| バックグラウンド |
|---|
Members of the Janus family of tyrosine kinases (Jak1, Jak2, Jak3, and Tyk2) are activated by ligands binding to a number of associated cytokine receptors (1). Upon cytokine receptor activation, Jak proteins become autophosphorylated and phosphorylate their associated receptors to provide multiple binding sites for signaling proteins. These associated signaling proteins, such as Stats (2), Shc (3), insulin receptor substrates (4), and focal adhesion kinase (FAK) (5), typically contain SH2 or other phospho-tyrosine-binding domains.
| 使用例 | |
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| 製品をご使用いただいて研究を発表されましたら、ぜひお知らせください。 |
本製品は試験研究用です。

