#75205 Calbindin (D1I4Q) XP® Rabbit mAb (Alexa Fluor® 647 Conjugate)
|Calbindin (D1I4Q) XP® Rabbit mAb (Alexa Fluor® 647 Conjugate) recognizes endogenous levels of total calbindin protein.|
|Monoclonal antibody is produced by immunizing animals with recombinant protein specific to the amino terminus of human calbindin protein.|
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Calcium-binding proteins of different subfamilies regulate the second messenger calcium. Calbindin, calmodulin, S-100, parvalbumin and troponin C are members of the low molecular weight calcium-binding protein family (1). Calbindin is expressed in discrete neuronal populations within the CNS and is thought to act as an intracellular calcium buffering protein. Most Purkinje cells express calbindin, which is expressed when neurons start to migrate and differentiate. In contrast, other calcium buffering proteins, such as parvalbumin, are expressed later during development and in parallel with increasing neuronal activity (2).
|13176 Calbindin (D1I4Q) XP® Rabbit mAb|
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